Thursday, April 7, 2011

NDM 1 what is it?

  • NDM-1(New Delhi metallo-ß-lactamase-1) is the gene (the DNA code) found in some types of bacteria
  • This gene makes the bacteria produce an enzyme called a carbapenemase - making carbepenem antibiotics ineffective (as well as virtually all other antibiotics).
  • Carbepenem antibiotics are extremely powerful and used to fight highly resistant bacteria (when other antibiotics have not worked).
  • There are no current antibiotics to combat NDM-1
  • There is no research in the pipeline on drugs to combat NDM-1
  • A bacterium with the NDM-1 DNA code has the potential to be resistant to all our current antibiotics, as well as new antibiotics which may come into the market in the near future.

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